Ammonia → HCID 13377346, compound

HRID 364235Notes

Reaction equation

HRID 364235 reaction equation
Cl[C:2]1[N:7]2[C:8]([CH2:11][CH2:12][CH3:13])=[N:9][CH:10]=[C:6]2[CH:5]=[C:4]([Cl:14])[N:3]=1.[NH3:15]>>[NH2:15][C:2]1[N:7]2[C:8]([CH2:11][CH2:12][CH3:13])=[N:9][CH:10]=[C:6]2[CH:5]=[C:4]([Cl:14])[N:3]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 217939465,7-Dichloro-3-propylimidazo[1,5-c]pyrimidine

Product 1

HCID 13377346HCID 13377346, compound

Procedure

Using the method of Example 39, 5,7-dichloro-3-(n-propyl)imidazo[1,5-c]pyrimidine (from Example 36) was reacted with ammonia to provide white solid 5-amino-7-chloro-3-(n-propyl)imidazo[1,5-c]pyrimidine, m.p. 160°-161° C. (dec.). Analysis: Calculated for C9H11ClN4 : %C, 51.3; %H, 5.3; %N, 26.6; Found %C, 51.5; %H, 5.2; %N, 26.9.

Sources & evidence

ORD record
ord-6232ce9f63194636bb89710e52627f73
Source dataset
uspto-grants-1986_08
Patent number
US04604466

Reaction notes

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