Formic Acid → HCID 21793931, compound

HRID 364242Notes

Reaction equation

HRID 364242 reaction equation
[NH2:1][CH2:2][C:3]1[N:8]=[C:7]([S:9][CH3:10])[N:6]=[C:5]([S:11][CH3:12])[CH:4]=1.[CH:13](O)=[O:14]>>[CH3:10][S:9][C:7]1[N:6]=[C:5]([S:11][CH3:12])[CH:4]=[C:3]([CH2:2][NH:1][CH:13]=[O:14])[N:8]=1

Participants

3

Reactant 2

HCID 284Formic AcidHCID 13339913HCID 13339913, compound

Product 1

HCID 21793931HCID 21793931, compound

Procedure

Using the method of Example 5, 6-aminomethyl-2,4-bis(methylthio)pyrimidine from Example 1, part E or Example 8 was reacted with formic acid to provide 2,4-bis(methylthio)-6-formylaminomethylpyrimidine as a light yellow solid. The structural assignment was confirmed by infrared and nuclear magnetic resonance spectral analyses.

Sources & evidence

ORD record
ord-72be3b8b449b42099be7edd7152214e7
Source dataset
uspto-grants-1986_08
Patent number
US04604466

Reaction notes

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