HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → 3-(3,4-Dimethoxyphenyl)propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Veratraldehyde | HCID 8419 | — |
| Reactant | 2,2-Dimethyl-1,3-dioxane-4,6-dione | HCID 16249 | — |
| Product | 3-(3,4-Dimethoxyphenyl)propionic acid | HCID 75019 | — |
Reaction Steps
After dropping 20.4 g (23.7 ml, 0.24 mol) of piperidine to 27.6 g (22.6 ml, 0.6 mol) of formic acid under stirring and cooling, 7.2 g (0.05 mol) of Meldrum's acid and 8.3 g (0.05 mol) of veratraldehyde were added to the above mixture, then the procedure of Example 35 was followed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05414108 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-02825bd7e2084cfab618e7b23a060c3b |
| Source note | uspto-grants-1995_05 |