HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 2-(2-aminothiazol-4-yl)-2-pentyloxyiminoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | Sodium Acetate Trihydrate | HCID 23665404 | — |
| Reactant | Ethyl 4-chloro-3-oxo-2-[(pentyloxy)imino]butanoate | HCID 53992771 | — |
| Solvent | Water | HCID 962 | — |
| Product | Ethyl 2-(2-aminothiazol-4-yl)-2-pentyloxyiminoacetate | HCID 54426052 | 52.1% |
Reaction Steps
Ethyl 2-pentyloxyimino-4-chloro-3-oxobutyrate (syn isomer, 51.1 g.), thiourea (14.7 g.), sodium acetate trihydrate (26.4 g.), ethanol (175 ml.) and water (125 ml.) were treated in a similar manner to that of Example F-(3) to give ethyl 2-(2-aminothiazol-4-yl)-2-pentyloxyiminoacetate (syn isomer, 28.7 g.), mp 86° to 88° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04604456 |
| Source dataset | uspto-grants-1986_08 |
| ORD ID | ord-0e714082046b4e8f802ccb7a55a1dcb4 |
| Source note | uspto-grants-1986_08 |