Acetic Anhydride → HCID 53969544, compound

HRID 364606Notes

Reaction equation

HRID 364606 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[N:11][O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:8]([OH:10])=[O:9])[N:6]=1.[C:21](OC(=O)C)(=[O:23])C>C(O)=O>[CH:21]([NH:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[N:11][O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:8]([OH:10])=[O:9])[N:6]=1)=[O:23]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 53874944HCID 53874944, compound

Product 1

HCID 53969544HCID 53969544, compoundYield 97.4%

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

2-(2-Aminothiazol-4-yl)-2-n-octyloxyiminoacetic acid (syn isomer, 20 g.), acetic anhydride (27.3 g.) and formic acid (12.3 g.) were treated in a similar manner to that of Example F-(5) to give 2-(2-formamidothiazol-4-yl)-2-n-octyloxyiminoacetic acid (syn isomer, 21.3 g.), mp. 122° C. (dec.).

Sources & evidence

ORD record
ord-24eba3a6cb564a5ca86f69f33834bb08
Source dataset
uspto-grants-1986_08
Patent number
US04604456

Reaction notes

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