HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 1-(hydroxymethyl)-4-(iminophenyl)-9,10-dimethoxy-1,6,7,11b-tetrahydro-2H-[1,3]oxazino[4,3-a]isoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 1-(hydroxymethyl)-2-(methylthio)-9,10-dimethoxy-1,6,7,11b-tetrahydro-2H-[1,3]oxazino[4,3-a]isoquinoline iodide | HCID 20239376 | — |
| Product | 1-(hydroxymethyl)-4-(iminophenyl)-9,10-dimethoxy-1,6,7,11b-tetrahydro-2H-[1,3]oxazino[4,3-a]isoquinoline | HCID 86740952 | — |
Reaction Steps
To a solution of 4.51 g (0.01 mole) of 1-(hydroxymethyl)-2-(methylthio)-9,10-dimethoxy-1,6,7,11b-tetrahydro-2H-[1,3]oxazino[4,3-a]isoquinoline iodide in ethanol 9.3 g (0.10 mole) of aniline are added, and the reaction mixture is boiled for 3 hours. Upon cooling the product separates from the mixture in crystalline form.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04605653 |
| Source dataset | uspto-grants-1986_08 |
| ORD ID | ord-b87bcfcaf5e241aeb4a6cf6bd0cc02db |
| Source note | uspto-grants-1986_08 |