HuagongsheHuagongshe Chemistry Print Report · For research reference only
Barium → 4-(1H-Imidazol-2-yl)-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Barium | HCID 5355457 | — |
| Reactant | 4-(4,5-dihydro-1H-imidazol-2-yl)pyridine | HCID 11159387 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(1H-Imidazol-2-yl)-pyridine | HCID 316817 | 68.1% |
Reaction Steps
2-(4-pyridyl)-imidazoline (7.0 g, 0.047M) and barium mangnate (52.5 g) in CH2Cl2 (500 ml) were refluxed with stirring for 24 hrs. The reaction mixture was then filtered through diatomaceous earth, washed with methylene chloride and then ethylacetate. The combined filtrates were concentrated and crystallized from ethylacetate-petroleum ether to give 4-(1H-imidazol-2-yl)pyridine (4.7 g, 67% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04605744 |
| Source dataset | uspto-grants-1986_08 |
| ORD ID | ord-8d2006b4e8cb47d7b5b819625280b916 |
| Source note | uspto-grants-1986_08 |