HCID 53805657, compound → HCID 20239883, compound

HRID 364777Notes

Reaction equation

HRID 364777 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[C:9]([OH:26])([C:12]1[CH:17]=[CH:16][C:15]([O:18][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:14][CH:13]=1)[CH:10]=[CH2:11].[H][H]>[Ni].C(O)C>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[C:9]([C:12]1[CH:17]=[CH:16][C:15]([O:18][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:14][CH:13]=1)([OH:26])[CH2:10][CH3:11]

Participants

5

Reactant 2

HCID 53805657HCID 53805657, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 20239883HCID 20239883, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

10.3 g. of 1-(2,5-dimethylphenyl)-1-(4-benzyloxyphenyl)-allyl alcohol are dissolved in 110 ml. of ethanol and the reaction mixture is hydrogenated under atmospheric pressure, in the presence of 3.5 g. of Raney nickel catalyst. After uptake of the calculated amount of hydrogen is complete, the catalyst is filtered off. Ethanol is distilled off under reduced pressure. As a residue 9 g. of the named compound are obtained as a viscous oil, boiling at 190°-192° C./26.6 Pa.

Workup

  1. filtrationthe catalyst is filtered off
  2. distillationEthanol is distilled off under reduced pressure
  3. customof the named compound are obtained as a viscous oil, boiling at 190°-192° C./26.6 Pa

Sources & evidence

ORD record
ord-b2dc232f4b5b4344b4139aee2fb1b2b3
Source dataset
uspto-grants-1986_08
Patent number
US04605785

Reaction notes

Loading…