Hydrochloric Acid → HCID 178526577, compound

Participants

Reaction Steps

The reactions of Equation 36 above can be run according to similar procedures described in E. Hoggarth, J. Chem. Soc., 4811 (1952). Thus, in reaction 36a, 2-nitrobenzhydrazide XLVIII is reacted with carbon disulfide in pyridine solvent at 25° to 80° C. for about 4 to 16 hours, followed by addition of water and acidification with hydrochloric acid to form a 2-mercapto-5-(2-nitrophenyl)-1,3,4-oxadiazole of Formula (L). In reaction 36b, L is reacted with sodium hydroxide and methyl iodide in water at 0° to 30° C. for 0.2 to 1 hour to form Xk".

Provenance & Evidence