Methylhydrazine → HCID 3544471, compound

HRID 364848Notes

Reaction equation

HRID 364848 reaction equation
[CH3:1][N:2](C)[CH:3]=[C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-:15])=[O:14])[CH:5]=O.C[NH:18]N>C1(C)C=CC=CC=1>[CH3:1][N:2]1[CH:3]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[N+:13]([O-:15])=[O:14])[CH:5]=[N:18]1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 3557290HCID 3557290, compound

Product 1

HCID 3544471HCID 3544471, compoundYield 92.1%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of 60 g of 3-(dimethylamino)-2-(2-nitrophenyl)acrolein (see Example 10) and 16.1 g of methylhydrazine in 200 ml of toluene was refluxed for 10 hours, then concentrated to dryness in vacuo. The residue was recrystallized from 1-chlorobutane/hexane (about 1:1) to yield 51 g of the title compound; m.p. 41°-44° C.

Workup

  1. concentrationconcentrated to dryness in vacuo
  2. customThe residue was recrystallized from 1-chlorobutane/hexane (about 1:1)

Sources & evidence

ORD record
ord-dca3d271e55d47d7942848dd70d7404a
Source dataset
uspto-grants-1986_08
Patent number
US04606755

Reaction notes

Loading…