HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 364895Generated: October 25, 2026
Chlorosulfonic acid → 3-Methoxy-5,6,7,8-tetrahydronaphthalene-2-sulfonyl chloride
https://huagongshe.com/reaction/364895
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chlorosulfonic acid | HCID 24638 | — |
| Reactant | 6-Methoxytetralin | HCID 74414 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Methoxy-5,6,7,8-tetrahydronaphthalene-2-sulfonyl chloride | HCID 13210342 | — |
Reaction Steps
118 g (0.73 mole) of 5,6,7,8-tetrahydro-2-naphthol methyl ether are dissolved in 320 ml of methylene chloride, and 177 ml of chlorosulfonic acid in 160 ml of methylene chloride are added. The mixture is stirred for 10 minutes at 5° C. and is poured into ice water. The organic phase is separated off and dried with MgSO4. The solvent is removed by evaporation and the residue is recrystallized from acetone/petroleum ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04607030 |
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| Source dataset | uspto-grants-1986_08 |
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| ORD ID | ord-9bacb43ee4cb43199d5ffc4dd58e4573 |
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| Source note | uspto-grants-1986_08 |
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