反应详情

43 g (0.2 mole) of 2-aminomethyl-4-(1,1-dimethylethyl)-phenol hydrochloride are suspended in 400 ml of 1,4-dioxane, and 40 ml of pyridine are added. 40 ml (0.55 mole) of acetyl chloride are added dropwise while stirring and cooling with ice. The mixture is then stirred for 2.5 hours at 90° and poured into ice water, and the precipitate which has crystallized out is filtered off with suction.

1. temperaturecooling with ice
2. stirringThe mixture is then stirred for 2.5 hours at 90°
3. customthe precipitate which has crystallized out
4. filtrationis filtered off with suction