Ethylamine → 2-Aminomethyl-4-(1,1-dimethylethyl)-6-ethylsulfamoylphenol hydrochloride

HRID 364902Notes

Reaction equation

C([NH:4][CH2:5][C:6]1[CH:11]=[C:10]([C:12]([CH3:15])([CH3:14])[CH3:13])[CH:9]=[C:8]([S:16]([Cl:19])(=[O:18])=[O:17])[C:7]=1[OH:20])(=O)C.[CH2:21]([NH2:23])[CH3:22]>>[ClH:19].[NH2:4][CH2:5][C:6]1[CH:11]=[C:10]([C:12]([CH3:13])([CH3:14])[CH3:15])[CH:9]=[C:8]([S:16](=[O:17])(=[O:18])[NH:23][CH2:21][CH3:22])[C:7]=1[OH:20]

Participants

Reactant 2

HCID 6341Ethylamine

HCID 132103492-Acetamidomethyl-6-chlorosulfonyl-4-(1,1-dimethylethyl)-phenol

Product 1

HCID 212969392-Aminomethyl-4-(1,1-dimethylethyl)-6-ethylsulfamoylphenol hydrochloride

Procedure

This compound is prepared analogously to Examples 11c and 11d from 2-acetamidomethyl-6-chlorosulfonyl-4-(1,1-dimethylethyl)-phenol and ethylamine.

Sources & evidence

ORD record: ord-a72f68c71fc2412c9148e358d4876460
Source dataset: uspto-grants-1986_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04607030

Reaction notes

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