HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Carbethoxycinnamic acid → 4-Ethoxycarbonylbenzenepropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Carbethoxycinnamic acid | HCID 54220427 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Ethoxycarbonylbenzenepropanoic acid | HCID 21821690 | 46% |
Reaction Steps
A solution of 4-carbethoxycinnamic acid (4.9 g) in EtOH (120 ml) was hydrogenated over 5% Rh/C (485 mg) at atmospheric pressure for 21 hr. The solution filtered and stripped. The residue was crystallized from cyclohexane to afford 2.23 g (46%) of the title compound as white crystals; mp 108.5°-110.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05414132 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-5c92a31500f442ccacf5c8bb99184d6e |
| Source note | uspto-grants-1995_05 |