反应详情

4-Bromobenzenesulfonyl chloride (14.05 g, 55 mmol) was added to a stirred solution of benzylamine (5.36 g, 50 mmol) and pyridine (400 ml) under nitrogen at room temperature. The resulting reaction mixture was stirred for 1 hr; then it was poured onto ice/water (800 ml) to form a yellow precipitate which was filtered and recrystallized from EtOH/water to give 9.44 g (53%) of the title compound as off-white needles, mp 116°-117° C.

1. customThe resulting reaction mixture
2. additionthen it was poured onto ice/water (800 ml)
3. customto form a yellow precipitate which
4. filtrationwas filtered
5. customrecrystallized from EtOH/water