2-Nitrophenol → HCID 20239170, compound

HRID 365037Notes

Reaction equation

HRID 365037 reaction equation
[C:1]([NH:4][C:5]1[C:6]([I:25])=[C:7]([C:16]([I:24])=[C:17]([NH:20][C:21](=[O:23])[CH3:22])[C:18]=1[I:19])[C:8]([NH:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[O:9])(=[O:3])[CH3:2].[N+:26]([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1O)([O-:28])=[O:27].C1(N=C=NC2CCCCC2)CCCCC1>>[N+:26]([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[O:14][C:13](=[O:15])[CH2:12][CH2:11][NH:10][C:8](=[O:9])[C:7]1[C:6]([I:25])=[C:5]([NH:4][C:1](=[O:3])[CH3:2])[C:18]([I:19])=[C:17]([NH:20][C:21](=[O:23])[CH3:22])[C:16]=1[I:24])([O-:28])=[O:27]

Participants

4

Reactant 3

HCID 69472-NitrophenolHCID 10868DicyclohexylcarbodiimideHCID 20239184HCID 20239184, compound

Product 1

HCID 20239170HCID 20239170, compound

Procedure

Following the procedure of example 33 the product is synthesized from 13.7 g (20 mMol) N-(3,5-diacetamido-2,4,6-triiodobenzoyl)-β-alanine, 3.5 g (25 mMol)-o-nitrophenol and 5 g (24 mMol) N,N'-dicyclohexylcarbodiimide. Yield 11 g (68%).

Sources & evidence

ORD record
ord-a3db7dd371a6457a956c55ade21e6b92
Source dataset
uspto-grants-1986_08
Patent number
US04607123

Reaction notes

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