Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl acetylenedicarboxylate → Dimethyl 3-thienylaminobutenedioate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl acetylenedicarboxylate | HCID 12980 | — |
| 반응물 | Thiophen-3-amine | HCID 640543 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Dimethyl 3-thienylaminobutenedioate | HCID 56624739 | — |
반응 단계
3-Aminothiophene is redissolved in methanol (500 mL) cooled in an ice bath and dimethylacetylenedicarboxylate (80 g; 0.50 mol) is added dropwise. The mixture is stirred at room temperature for 15 hours and 30 minutes, the methanol removed under reduced pressure and 1,2-dichloroethane is added. This solvent is also evaporated off to give dimethyl 3-thienylaminobutenedioate as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04608079 |
| 출처 데이터셋 | uspto-grants-1986_08 |
| ORD ID | ord-d032adb4cc5c46af9c30c28a3ad717af |
| 출처 메모 | uspto-grants-1986_08 |