4-(Dimethylamino)Benzaldehyde → HCID 70455102, compound

Participants

Reaction Conditions

Reaction Steps

2-Picoline (9.3 g, 0.1 mole) and benzyl bromide (17.1 g, 0.1 mole) were refluxed in isopropanol (50 ml) overnight. The solvent was evaporated giving an oil which was heated at 100° C. for six hours. The resulting crude oil (8.0 g, 0.03 mole) and 4-dimethylaminobenzaldehyde (4.6 g, 0.03 mole) were refluxed in methanol (50 ml) in the presence of piperidine (0.2 ml) under nitrogen for three hours. On cooling dark-coloured crystals were obtained which were collected to give 1-benzyl-2-[4-(dimethylamino)styryl]pyridinium bromide (6.8 g), melting point 250°-251° C.

Provenance & Evidence