Methyl 4-amino-5-methylthiophene-3-carboxylate → HCID 20237893, compound

HRID 365198Notes

Reaction equation

HRID 365198 reaction equation
[CH3:1][C:2]1[S:3][CH:4]=[C:5]([C:8](OC)=[O:9])[C:6]=1[NH2:7].[H-].[Al+3].[Li+].[H-].[H-].[H-]>C(OCC)C>[NH2:7][C:6]1[C:5]([CH2:8][OH:9])=[CH:4][S:3][C:2]=1[CH3:1]

Participants

4

Reactant 2

HCID 11401021Methyl 4-amino-5-methylthiophene-3-carboxylateHCID 21226445Aluminium lithium hydride

Product 1

HCID 20237893HCID 20237893, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

m.p. 70°-71° C. by the reduction of methyl 2-methyl-3-aminothiophene-4-carboxylate with lithium aluminum hydride in diethyl ether.

Sources & evidence

ORD record
ord-0fe0a5752f6c42338042743d1335b2b5
Source dataset
uspto-grants-1986_08
Patent number
US04608383

Reaction notes

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