反应详情

3.6 g. Phenyl glycidyl ether and 9.0 g. 5-methyl-7-(2-aminoethylamino)-s-triazolo[1,5-a]pyrimidine are dissolved in dimethyl sulphoxide and left to stand for 48 hours at 45° C. The reaction mixture is then poured into water, extracted with methylene chloride, dried and purified chromatographically in the manner described in Example 28. There are obtained 2.0 g. (24% of theory) of the desired product in the form of colorless crystals; m.p. 126°-127° C., after recrystallization from isopropyl alcohol.

1. waitleft
2. extractionextracted with methylene chloride
3. customdried
4. custompurified chromatographically in the manner
5. customThere are obtained 2.0 g