HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexane → HCID 23291342, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexane | HCID 8078 | — |
| Reactant | Ammonium formate | HCID 2723923 | — |
| Reactant | HCID 23291344 | HCID 23291344 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 23291342 | HCID 23291342 | — |
Reaction Steps
A solution of 6-benzyloxymethyl-5-(2-methoxymethoxy-4-methoxyphenyl)-4-propoxy-pyrimidine (3.41 g, 8.04 mmol), cyclohexane (35 ml), Pd(OH)2 (3.4 g) and ammonium formate (3.4 g) in ethanol (100 ml) was kept at reflux for 3 d. After cooling the mixture was filtered through celite and concentrated to an oil. (2.42 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06127371 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-4cf971c7edac4152886a14c08f2ab33f |
| Source note | uspto-grants-2000_10 |