HCID 23291432, compound → HCID 86755873, compound

HRID 365395Notes

Reaction equation

HRID 365395 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:14]=1[S:13][CH2:12][CH:11]=[CH:10]2)=[O:4]>C(O)C>[CH3:1][O:2][C:3]([C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:14]=1[S:13][CH2:12][CH2:11][CH2:10]2)=[O:4]

Participants

3

Reactant 1

HCID 23291432HCID 23291432, compound

Product 1

HCID 86755873HCID 86755873, compoundYield 68%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Methyl-2H-thiochromene-8-carboxylate (1.83 g, 8.88 mmol) was dissolved in ethanol (100 ml) and treated with 10% PdC (1.5 g). The mixture was then hydrogenated at atmospheric pressure at room temperature. After 19 h the reaction mixture was filtered through celite and evaporated under reduced pressure to give a colourless oil which was dried in vacuo to give the title compound (1.25 g, 68%)

Workup

  1. customwas then hydrogenated at atmospheric pressure at room temperature
  2. filtrationAfter 19 h the reaction mixture was filtered through celite
  3. customevaporated under reduced pressure
  4. customto give a colourless oil which
  5. customwas dried in vacuo

Sources & evidence

ORD record
ord-9680596c3be5453198746b0c0ed7cdcb
Source dataset
uspto-grants-2000_10
Patent number
US06127379

Reaction notes

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