L-Lysine → HCID 131722019, compound

HRID 365430Notes

Reaction equation

N[C@H:2]([C:8](O)=[O:9])CCCCN.[NH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C@H:16]([NH:20][C:21]([C@H:23]([N:30]([CH3:55])[C:31]([C@H:33]([NH:45][C:46](=[O:54])/[CH:47]=[CH:48]/[CH2:49][C:50]([NH2:53])([CH3:52])[CH3:51])[CH2:34][C:35]1[CH:44]=[CH:43][C:42]2[C:37](=[CH:38][CH:39]=[CH:40][CH:41]=2)[CH:36]=1)=[O:32])[CH2:24][C:25]1[S:26][CH:27]=[CH:28][CH:29]=1)=[O:22])[C:17](=[O:19])[NH2:18]>>[C:8]([NH:11][CH2:12][CH2:13][CH2:14][CH2:15][C@H:16]([NH:20][C:21]([C@H:23]([N:30]([CH3:55])[C:31]([C@H:33]([NH:45][C:46](=[O:54])/[CH:47]=[CH:48]/[CH2:49][C:50]([NH2:53])([CH3:52])[CH3:51])[CH2:34][C:35]1[CH:44]=[CH:43][C:42]2[C:37](=[CH:38][CH:39]=[CH:40][CH:41]=2)[CH:36]=1)=[O:32])[CH2:24][C:25]1[S:26][CH:27]=[CH:28][CH:29]=1)=[O:22])[C:17](=[O:19])[NH2:18])(=[O:9])[CH3:2]

Participants

Reactant 2

HCID 5962L-Lysine

HCID 70293679HCID 70293679, compound

Product 1

HCID 131722019HCID 131722019, compound

Procedure

This compound was prepared by acetylation of the epsilon amino group in the lysine fragment using the general method described above and using the compound prepared in example 22 as starting material.

Sources & evidence

ORD record: ord-465bb073b70543838389f1789d82717a
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127341

Reaction notes

Loading…