HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-(3-Chlorophenyl)ethane-1,2-diol → (s)-(2-(3-Chlorophenyl)-2-hydroxyethyl)oxocarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-(3-Chlorophenyl)ethane-1,2-diol | HCID 10130180 | — |
| Reactant | (s)-(2-(3-Chlorophenyl)-2-carbamoyloxyethyl)oxocarboxamide | HCID 131721943 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (s)-(2-(3-Chlorophenyl)-2-hydroxyethyl)oxocarboxamide | HCID 131721942 | 25% |
Reaction Steps
(S)-(2-(3-Chlorophenyl)-2-carbamoyloxyethyl)oxocarboxamide (1.36 g, yield 25%, m.p. 117-119° C., [α]D =12.88 (c=2.30, MeOH) was prepared using the same synthetic method described in Example 20, except (S)-1-m-chlorophenyl-1,2-ethanediol was used instead of (DL)-1-m-chlorophenyl-1,2-ethanediol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06127412 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-6cfca9cd125a4350a3f7dbb8723965ae |
| Source note | uspto-grants-2000_10 |