4-(1-Methylpyrrol-2-ylmethyl)nitrobenzene → 4-(1-Methylpyrrol-2-yl-methyl)aniline

Participants

Reaction Steps

4-(1-Methylpyrrol-2-ylmethyl)nitrobenzene (500 mg, 2.31 mmol) [prepared as described in Example 21, Step (b)], was dissolved in ethyl acetate and subjected to hydrogenation over 5% Pd/C (50 mg) at ambient temperature and atmospheric pressure. After 3 h the mixture was filtered and the filtrate was concentrated to give 4-(1-methylpyrrol-2-yl-methyl)aniline (430 mg, 100%) as a yellow oil. ##STR63##

Provenance & Evidence