Hydroxylamine → HCID 86751692, compound

Participants

Reaction Steps

A solution of 7-nitrotetralone (4.20 g, 22.0 mmol) in methanol (100 mL) was cooled to 0° C., and hydroxylamine (1.68 g, 23.2 mmol) and sodium acetate (3.69 g, 46.4 mmol) were added. The reaction was then stirred at room temperature for 12 h. The methanol was evaporated at reduced pressure and dichloromethane (100 mL) was added. The mixture was washed with water, dried over NaSO4 and evaporated at reduced presure to yield the title compound (4.37 g, 97%). MS (DCI/NH3) m/e 207 [M+H]+.

Provenance & Evidence