HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetyl chloride → 4-Bromoacetyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetyl chloride | HCID 89602 | — |
| Reactant | 7-Methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine | HCID 11805628 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 4-Bromoacetyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine | HCID 15291645 | 51.5% |
Reaction Steps
7-Methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (3.0 g), triethylamine (3.1 g) and bromoacetyl chloride (3.2 g) were reacted in the same manner as in Experimental Example 1 to give 4-bromoacetyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (2.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05416066 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-f2d9bc7a547848ad9da613d6416d1ac8 |
| Source note | uspto-grants-1995_05 |