HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 4-Acryloyl-2-chloro-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 1-(7-Methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)prop-2-en-1-one | HCID 11391024 | — |
| Product | 4-Acryloyl-2-chloro-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine | HCID 15291647 | 52.7% |
Reaction Steps
4-Acryloyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (4.0 g) and sulfuryl chloride (2.3 g) were reacted in the same manner as in Experimental Example 7 to give 4-acryloyl-2-chloro-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (2.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05416066 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-dd3db43f1983436cb60adb96c8a9a256 |
| Source note | uspto-grants-1995_05 |