2,4,6-Trimethylpyridine → HCID 23292931, compound

Participants

Reaction Conditions

Reaction Steps

Collidine (1), (5 g, 41.3 mmol) in dry tetrahydrofuran was added dropwise and the mixture was stirred for 60 min at -40° C. To this stirred mixture 1-benzoxy-2-bromethane (Tetrahedron Lett. 28, 2639-42, 1979) (8.24 g, 39.2 mmol) dissolved in dry tetrahydrofuran (20 ml) was added dropwise during 30 min and the reaction mixture was stirred overnight.

Provenance & Evidence