Butylamine → Melamine, butyl- (8CI)

HRID 365705Notes

Reaction equation

HRID 365705 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[N:5]=[C:4](Cl)[N:3]=1.[CH2:10]([NH2:14])[CH2:11][CH2:12][CH3:13]>O>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH:14][CH2:10][CH2:11][CH2:12][CH3:13])[N:3]=1

Participants

4

Reactant 2

HCID 8007ButylamineHCID 188311,3,5-Triazine-2,4-diamine, 6-chloro-

Product 1

HCID 197831Melamine, butyl- (8CI)Yield 96%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 14.5 g (0.1 mol) of 2,4-diamino-6-chloro-1,3,5-triazine prepared in Reference Example 1, 100 mL of water, and 29.2 g (0.4 mol) of butylamine was warmed with stirring and allowed to react finally at a reflux temperature for 6 hours. After cooling the reaction mixture, the product was filtered and washed sufficiently with a large amount of water and then washed with toluene. The filtrate was dried at 70° C. for 6 hours in vacuum to obtain 17.5 g (yield 96%) of the titled compound. Melting point: 167° C.

Workup

  1. temperaturewas warmed
  2. customto react finally at a reflux temperature for 6 hours
  3. temperatureAfter cooling the reaction mixture
  4. filtrationthe product was filtered
  5. washwashed sufficiently with a large amount of water
  6. washwashed with toluene
  7. customThe filtrate was dried at 70° C. for 6 hours in vacuum

Sources & evidence

ORD record
ord-4d13075d185f40a38a8444d99b7d9997
Source dataset
uspto-grants-2000_10
Patent number
US06127538

Reaction notes

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