Ethylamine → 4-(Ethylamino)benzonitrile

HRID 365718Notes

Reaction equation

F[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.[CH2:10]([NH2:12])[CH3:11]>>[CH2:10]([NH:12][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1)[CH3:11]

Participants

Reactant 2

HCID 6341Ethylamine

HCID 145174-Fluorobenzonitrile

Product 1

HCID 232930934-(Ethylamino)benzonitrile

Procedure

According to a similar manner to that in Reference Example 1, the title compound was synthesized from 4-fluorobenzonitrile and 70% aqueous ethylamine solution.

Sources & evidence

ORD record: ord-c6332880f5504329a7d26ac369b34eb7
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127541

Reaction notes

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