Ethanolamine → 4-[(2-hydroxyethyl)amino]benzonitrile

HRID 365722Notes

Reaction equation

F[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.[CH2:10]([CH2:12][NH2:13])[OH:11]>>[OH:11][CH2:10][CH2:12][NH:13][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 700Ethanolamine

HCID 145174-Fluorobenzonitrile

Product 1

HCID 2946154-[(2-hydroxyethyl)amino]benzonitrile

Procedure

According to a similar manner to that in Reference Example 3, the title compound was synthesized from 4-fluorobenzonitrile and ethanolamine.

Sources & evidence

ORD record: ord-6200477743064507835a80bbeec32886
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127541

Reaction notes

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