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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 365732Generated: October 31, 2026

1-Methylpiperazine → 3-(4-methylpiperazin-1-yl)benzonitrile

https://huagongshe.com/reaction/365732

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant3-FluorobenzonitrileHCID 67880—
Product3-(4-methylpiperazin-1-yl)benzonitrileHCID 7164595—

Reaction Steps

According to a similar manner to that in Reference Example 17, the title compound was synthesized from 3-fluorobenzonitrile and 1-methylpiperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06127541
Source datasetuspto-grants-2000_10
ORD IDord-2541833ea9424f678a5f299664f4edca
Source noteuspto-grants-2000_10