4-Fluorobenzonitrile → HCID 23293033, compound

HRID 365741Notes

Reaction equation

HRID 365741 reaction equation
F[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.[OH:10][CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][NH:14][CH2:13]1>>[OH:10][CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][N:14]([C:2]2[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=2)[CH2:13]1

Participants

3

Reactant 2

HCID 145174-FluorobenzonitrileHCID 107308Piperidin-3-ylmethanol

Product 1

HCID 23293033HCID 23293033, compound

Procedure

According to a similar manner to that in Reference Example 3, the title compound was synthesized from 4-fluorobenzonitrile and 3-hydroxymethylpiperidine.

Sources & evidence

ORD record
ord-8d7d20c9ed264551a2be9b802638c0d6
Source dataset
uspto-grants-2000_10
Patent number
US06127541

Reaction notes

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