2-Fluorobenzonitrile → HCID 17540059, compound

HRID 365745Notes

Reaction equation

F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[OH:10][CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][NH:14][CH2:13]1>>[OH:10][CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][N:14]([C:2]2[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=2[C:4]#[N:5])[CH2:13]1

Participants

Reactant 2

HCID 678552-Fluorobenzonitrile

HCID 107308Piperidin-3-ylmethanol

Product 1

HCID 17540059HCID 17540059, compound

Procedure

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and 3-(hydroxymethyl)piperidine.

Sources & evidence

ORD record: ord-af3c8eed09f147d69749182306c5cee2
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127541

Reaction notes

Loading…