Butylamine → 2-(Butylamino)benzonitrile

HRID 365749Notes

Reaction equation

F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH2:10]([NH2:14])[CH2:11][CH2:12][CH3:13]>>[CH2:10]([NH:14][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5])[CH2:11][CH2:12][CH3:13]

Participants

Reactant 2

HCID 8007Butylamine

HCID 678552-Fluorobenzonitrile

Product 1

HCID 232930142-(Butylamino)benzonitrile

Procedure

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and butylamine.

Sources & evidence

ORD record: ord-fec074e34a004b648d6ae06f60f2203f
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127541

Reaction notes

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