Isobutylamine → 2-[(2-Methylpropyl)amino]benzonitrile

HRID 365753Notes

Reaction equation

F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH2:10]([NH2:14])[CH:11]([CH3:13])[CH3:12]>>[CH3:12][CH:11]([CH3:13])[CH2:10][NH:14][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

Reactant 2

HCID 6558Isobutylamine

HCID 678552-Fluorobenzonitrile

Product 1

HCID 232930032-[(2-Methylpropyl)amino]benzonitrile

Procedure

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and isobutylamine.

Sources & evidence

ORD record: ord-506c2e75f68f4cc587c38124ba344ef1
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127541

Reaction notes

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