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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 365755Generated: November 1, 2026

2-Fluorobenzonitrile → 2-(4-Methyl-1,4-diazepan-1-yl)benzonitrile

https://huagongshe.com/reaction/365755

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorobenzonitrileHCID 67855—
Reactant1-MethylhomopiperazineHCID 228349—
Product2-(4-Methyl-1,4-diazepan-1-yl)benzonitrileHCID 23293055—

Reaction Steps

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and 4-methylhomopiperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06127541
Source datasetuspto-grants-2000_10
ORD IDord-101770408a8a4ff6be50f333faae6766
Source noteuspto-grants-2000_10