Diglycolamine → 2-[[2-(2-Hydroxyethoxy)ethyl]amino]benzonitrile

HRID 365756Notes

Reaction equation

F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[NH2:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][OH:16]>>[OH:16][CH2:15][CH2:14][O:13][CH2:12][CH2:11][NH:10][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

Reactant 2

HCID 13578Diglycolamine

HCID 678552-Fluorobenzonitrile

Product 1

HCID 232930822-[[2-(2-Hydroxyethoxy)ethyl]amino]benzonitrile

Procedure

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and 2-(2-aminoethoxy)ethanol.

Sources & evidence

ORD record: ord-d06d8e05edc9472aa986fc9733db39b1
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127541

Reaction notes

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