1,2,3,4-Tetrahydroisoquinoline → HCID 23293087, compound

HRID 365758Notes

Reaction equation

HRID 365758 reaction equation
F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH2:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:13][CH2:12][NH:11]1>>[CH2:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:13][CH2:12][N:11]1[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

3

Reactant 2

HCID 70461,2,3,4-TetrahydroisoquinolineHCID 678552-Fluorobenzonitrile

Product 1

HCID 23293087HCID 23293087, compound

Procedure

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and 1,2,3,4-tetrahydroisoquinoline.

Sources & evidence

ORD record
ord-5b8801b546684764be74a3f954795726
Source dataset
uspto-grants-2000_10
Patent number
US06127541

Reaction notes

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