(2-Thienylmethyl)amine → 2-(2-Thienylmethylamino)benzonitrile

HRID 365759Notes

Reaction equation

HRID 365759 reaction equation
F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[NH2:10][CH2:11][C:12]1[S:13][CH:14]=[CH:15][CH:16]=1>>[S:13]1[CH:14]=[CH:15][CH:16]=[C:12]1[CH2:11][NH:10][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

3

Reactant 2

HCID 34005(2-Thienylmethyl)amineHCID 678552-Fluorobenzonitrile

Product 1

HCID 232930462-(2-Thienylmethylamino)benzonitrile

Procedure

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and 2-aminomethylthiophene.

Sources & evidence

ORD record
ord-eb0990d86e4f45c28dfaa357b712ffd7
Source dataset
uspto-grants-2000_10
Patent number
US06127541

Reaction notes

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