2-Fluorobenzonitrile → 2-(2-Phenylaminoethylamino)benzonitrile

HRID 365760Notes

Reaction equation

F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[C:10]1([NH:16][CH2:17][CH2:18][NH2:19])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[C:10]1([NH:16][CH2:17][CH2:18][NH:19][C:2]2[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=2[C:4]#[N:5])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

Reactant 2

HCID 678552-Fluorobenzonitrile

HCID 742701,2-Ethanediamine, N1-phenyl-

Product 1

HCID 232929972-(2-Phenylaminoethylamino)benzonitrile

Procedure

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and N-phenylethylenediamine.

Sources & evidence

ORD record: ord-aa7d0ffbc3244408b18991d31f5a8a6a
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127541

Reaction notes

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