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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 365793Generated: October 27, 2026

3-Furaldehyde → Methyl 1,2,3,4-Tetrahydro-1-(3-Furyl)-9H-Pyrido(3,4-b) Indole-3-Carboxylate

https://huagongshe.com/reaction/365793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-FuraldehydeHCID 10351—
ReactantL-Tryptophan, methyl esterHCID 77980—
ProductMethyl 1,2,3,4-Tetrahydro-1-(3-Furyl)-9H-Pyrido(3,4-b) Indole-3-CarboxylateHCID 22677851—

Reaction Steps

The same method but starting from racemic tryptophan methyl ester and 3-furaldehyde gave the title compound as a yellow solid m.p.: 130° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06127542
Source datasetuspto-grants-2000_10
ORD IDord-e59c910517c840e9b2c741e83ed577f6
Source noteuspto-grants-2000_10