HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 2-Ethynylphenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Benzofuran | HCID 9223 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Ethynylphenol | HCID 138415 | 54% |
Reaction Steps
In the process described in Bull. Chem. Soc. Japan 29, 470-1(1956), benzofuran is heat-refluxed in the presence of pyridine and metallic sodium and thereafter treated with water to obtain 2-hydroxyphenylacetylene in 54% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06127583 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-4583fc4ca99148e2b79a6e400394a2f8 |
| Source note | uspto-grants-2000_10 |