Potassium bisulfate → HCID 86754505, compound

HRID 366017Notes

Reaction equation

[CH2:1]([O:3][CH:4]([O:40][CH2:41][CH3:42])[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]([CH2:26][C:27]([NH:29][C:30]2[CH:35]=[CH:34][C:33]([N:36]([CH3:38])[CH3:37])=[CH:32][CH:31]=2)=[O:28])([NH:15][C:16]([NH:18][C:19]2[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][CH:20]=2)=[O:17])[C:7]1=[O:39])[CH3:2].[S:43]([O-:47])([OH:46])(=[O:45])=[O:44].[K+:48]>>[S:43]([O-:47])([OH:46])(=[O:45])=[O:44].[K+:48].[CH2:1]([O:3][CH:4]([O:40][CH2:41][CH3:42])[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]([CH2:26][C:27]([NH:29][C:30]2[CH:31]=[CH:32][C:33]([N:36]([CH3:38])[CH3:37])=[CH:34][CH:35]=2)=[O:28])([NH:15][C:16]([NH:18][C:19]2[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][CH:20]=2)=[O:17])[C:7]1=[O:39])[CH3:2]

Participants

Reactant 2

HCID 516920Potassium bisulfate

HCID 15458214HCID 15458214, compound

Product 1

HCID 86754505HCID 86754505, compound

Procedure

The compound obtained in Example 180 was mixed with 1 equivalent of potassium hydrogensulfate, and the mixture was recrystallized from methanol to obtain the title compound as needles.

Workup

customthe mixture was recrystallized from methanol

Sources & evidence

ORD record: ord-cb46bf7fe83649fca1ed4b7abbf4f6ed
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127544

Reaction notes

Loading…