HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131722023, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 131722025 | HCID 131722025 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 131722023 | HCID 131722023 | — |
Reaction Steps
(R)-N2 -(Boc)-N5 -(Cbz)-(R)-N-[1-(4-methoxyphenyl)ethyl]ornithine amide (14.0 g; from step (a) above) in EtOAc (300 mL) was treated with EtOAc saturated with hydrogen chloride (HCl/EtOAc; 300 mL) at room temperature for 5 hours. The solution was concentrated to give the crude sub-title compound as a crushable foam (12.9 g) which was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06127414 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-32d5873851414f9b96b10c7bbce78f02 |
| Source note | uspto-grants-2000_10 |