Acetic Acid → HCID 131722031, compound

Participants

Reaction Steps

Prepared analogously to the method described in Example 1(e) above from (R)-N5 -(Cbz)-N2 -(diphenylacetyl)-(R)-N-[1-(4-hydroxyphenyl)ethyl]-ornithine amide (26.8 g; 46.23 mmol; from step (d) above), 10% Pd/C (2.5 g) and HOAc (1L; as opposed to HCl/MeOH) yielding 24.3 g of the sub-title compound (after azeotroping with toluene).

Provenance & Evidence