Dichloromethane → HCID 131722107, compound

Participants

Reaction Steps

To a solution of (R)-N2 -(diphenylacetyl)-(R)-N-[1-(4-hydroxyphenyl)ethyl]ornithine amide (2.0 g; 4.35 mmol; see Example 4(e) above) in CH2Cl2 (50 mL) was added benzoylisothiocyanate (0.59 mL; 4.35 mmol). The reaction mixture was stirred for 24 h at room temperature. The reaction was then concentrated in vacuo and the residue dissolved in EtOAc. The precipitated product, produced by addition of Et2O to the EtOAc solution, was collected and dried to afford 2.25 g (83%) of the sub-title compound as a white solid. The resultant material was used without further characterization.

Provenance & Evidence