反应详情

温度

80 °C

4.3 Grams of 4-hydroxy-2-fluorobenzoic acid and 8.4 g of anhydrous acetic acid were placed in a two-necked flask and mixed, and five drops of sulfuric acid was added with cooling with water. After heat generation terminated, the mixture was heated at 80° C. for 30 minutes. Then, the reaction mixture was discharged into cold water, and a precipitated crystal was recovered by filtration.

1. additionmixed
2. temperatureAfter heat generation
3. customterminated
4. filtrationa precipitated crystal was recovered by filtration