HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron trifluoride etherate → 7-Amino-5, 6-dihydro-3-chlorobenz-[c]-acridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | 2-Aminobenzonitrile | HCID 72913 | — |
| Reactant | 6-Chloro-1-tetralone | HCID 12291149 | — |
| Product | 7-Amino-5, 6-dihydro-3-chlorobenz-[c]-acridine | HCID 10588865 | — |
Reaction Steps
2-amino-1-cyano-benzene (5.0 g, 42.3 mmol), 6-chloro-3, 4-dihydro-[2H]-napthalen-1-one (Organon Laboratories) (8.8 g, 48.7 mmol) and boron trifluoride diethyl etherate (1M, 6.4 ml, 52.4 mmol) were treated according to the general procedure described herein to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06130228 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-2a63b073a34a435fa4999a775e34f4fe |
| Source note | uspto-grants-2000_10 |